Organic sulfuric acids and derivatives
Sigma Aldrich Fine Chemicals Biosciences Atropine sulfate salt mono5G
Atropine is isolated from Atropa belladonna Datura stramonium and Mandragora officinarum. It is a tertiary amine which acts as a cholinergic receptor antagonist.
Sigma Aldrich Fine Chemicals Biosciences Atropine sulfate salt mono25G
Atropine is isolated from Atropa belladonna Datura stramonium and Mandragora officinarum. It is a tertiary amine which acts as a cholinergic receptor antagonist.
Medchemexpress LLC Selumetinib sulfate | 943332-08-9 | 99.58% | C17H17BrClFN4O7S | 1 G
Selumetinib sulfate is a selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. It inhibits ERK1/2 phosphorylation and can penetrate the blood-brain barrier (BBB).
- Causes a time- and dose-dependent reduction in DNA synthesis and cell viability
- Induces growth arrest and apoptosis associated with the inactivation of ERK in primary cells
- Shows anti-proliferative effects through G0/G1 arrest
- Results in growth inhibition of cell lines containing B-Raf and Ras mutations
- Decreases the growth rate of xenografts in a dose-dependent manner
- Suppresses the growth of xenografts
- Inhibits ERK1/2 phosphorylation and growth of xenograft tumors in nude mice
- Tumor regressions observed in xenograft models
Medchemexpress LLC p-Cresyl sulfate | 3233-58-7 | 100.0% | 188.20 | 1 ML
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin known to cause renal damage and dysfunction. It exhibits antiproliferation activity and influences the expression of HIF-1α, VHL, and HIF-2α. This compound also induces epithelial-mesenchymal transition (EMT) and activates the JNK and p38 MAPK signaling pathways.
- Shows antiproliferation activity.
- Increases protein expression of HIF-1α and VHL.
- Decreases protein expression of HIF-2α.
- Induces epithelial-mesenchymal transition (EMT).
- Activates JNK and p38 MAPK signaling pathways.
Medchemexpress LLC FITC-dextran sulfate (MW 4kDa) | 4000.00 | 50 MG
FITC-dextran sulfate, 4 kDa, is a sodium dextran sulfate labeled with FITC. It has an average molecular weight of 4 kDa and is intended for research use only.
- Fluorescent dye
- Used as a biochemical assay reagent
- Used as a cell assay reagent
Medchemexpress LLC GC7 sulfate | 150417-90-6 | MFCD31619261 | 98.0% | 270.35 g/mol | C8H22N4O4S | 10 MG
GC7 sulfate is a small-molecule research reagent that inhibits deoxyhypusine synthase (DHPS). It is intended for laboratory research to probe hypusination, translation regulation, and cell-cycle pathways. The compound is supplied as a solid and as an aqueous solution, with documented solubility and storage recommendations to support biochemical and cellular assays.
- Inhibits deoxyhypusine synthase (DHPS) in vitro and in cell assays.
- High purity (98.0%).
- Available as solid and as a 10 mM aqueous solution.
- Soluble in water and PBS with ultrasonic warming and heat as needed.
- Recommended storage: sealed at 4°C; in solvent store at -80°C for long term.
- Suitable for biochemical and cellular research applications.
Medchemexpress LLC Heparan Sulfate-6-O- 100ug | 100ug
Heparan Sulfate-6-O-Sulfotransferase-3 (HS6ST3) is an enzyme involved in modifying heparan sulfate proteoglycan biosynthesis It is predicted to be a membrane-bound integral component HS6ST3 shows specific expression in the adult cortex (RPKM 1 3) and frontal lobe (RPKM 0 8) implying its potential role in determining the sulfation patterns of heparan sulfate in these contexts Heparan Sulfate-6-O-Sulfotransferase-3 Protein Mouse (HEK293 His) is the recombinant mouse-derived Heparan Sulfate-6-O-Sulfotransferase-3 protein expressed by HEK293 with N-His labeled tag
Medchemexpress LLC Heparan sulfate | 9050-30-0 | 593.47 (monomer) | C12H19NO20S3 (monomer) | 25 MG
Heparan sulfate is a complex, linear glycosaminoglycan used in biochemical and cell biology research to probe growth factor binding, cell signaling, and extracellular matrix interactions. Supplied as a dry material with reported monomer parameters for reference, it dissolves in aqueous buffers for use in assays and cell studies.
- Supports study of growth factor signaling, including FGFR and Wnt pathways.
- Suitable for extracellular matrix and proteoglycan research.
- Soluble in water and PBS; ultrasonic agitation may be required for complete dissolution.
- Monomer molecular formula C12H19NO20S3 and monomer molecular weight 593.47 for reference.
- Storage guidance available for sealed material and solutions to preserve stability.
TARGETMOL CHEMICALS INC GC7 SULFATE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS so GC7 inhibits the activation of eIF5A2 by inhibiting DHS activity. purity: 99%
Apexbio Technology LLC Vincristine sulfate 2068-78-2 100mg
Vincristine sulfate (CAS 2068-78-2) is a natural alkaloid isolated from the leaves of Catharanthus roseus structurally composed of two heterocyclic monomers vindoline and catharanthine connected by a bridging carbon It acts via inhibition of microtubule polymerization binding tubulin with a Ki of approximately 0 085 M In vitro vincristine demonstrates antiproliferative activity against B16 melanoma cells with an IC50 of 0 45 M The compound exhibits promising activity in research settings targeting diverse cancers including acute lymphoblastic leukemia acute non-lymphoblastic leukemia non-Hodgkin lymphoma Hodgkin disease and brain tumors
eMolecules 5689-83-8 | 1,2-Propanediol-cyclic sulfate | Combi-Blocks | MFCD08703327 | 138.140 | C3H6O4S | 97.000 | CC1COS(=O)(=O)O1 | 1g | 205392660
1,2-Propanediol-cyclic sulfate | Combi-Blocks | 5689-83-8 | MFCD08703327 | 138.140 | C3H6O4S | 97.000 | CC1COS(=O)(=O)O1 | 1g | 205392660
TARGETMOL CHEMICALS INC VORAPAXAR SULFATE 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist. purity: 99%
Medchemexpress LLC Sisomicin sulfate | 53179-09-2 | MFCD00058308 | 99.3% | 692.72 g/mol | C19H37N5O7 · 5/2 H2SO4 | 10 MG
Sisomicin sulfate is the analytical standard of the aminoglycoside antibiotic sisomicin, provided as a solid for laboratory analytical use. It is intended for qualitative and quantitative methods development and validation in HPLC, gas chromatography, and mass spectrometry.
- High purity: 99.3%.
- Molecular weight: 692.72 g/mol.
- Cas number: 53179-09-2.
- Solid form suitable for analytical weighing and dissolution.
- Available in small pack sizes, including 10 MG, for trace-level standard preparation.
- Recommended applications: HPLC, GC, and MS analytical standard and method development.
Medchemexpress LLC Vinblastine (sulfate) | 143-67-9 | 99.86% | 909.05 | 100 MG
Vinblastine sulfate is a cytotoxic alkaloid that targets various cancer types by inhibiting microtubule formation and suppressing nAChR (IC50 8.9 μM). It blocks mitosis (IC50 0.8 nM in HeLa cells), leading to cell apoptosis. For storage, keep sealed at 4°C, away from moisture and light. In solvent, store at -80°C for 6 months or -20°C for 1 month, similarly sealed. Room temperature shipping is suitable for durations under 2 weeks.
- Inhibits microtubule formation.
- Suppresses nAChR with an IC50 of 8.9 μM.
- Blocks mitosis, leading to cell apoptosis.
- Induces apoptosis via Bax/Bcl-2 imbalance.
- Suppresses NFκB expression and depresses NFκB-DNA binding activity.
- Triggers apoptosis by causing a loss of mitochondrial membrane potential and activating caspases.